Tests done for diagnosis include indirect hemagglutination, ELISA, and Casoni test. These tests support diagnosis of which liver pathology?

Tests done for diagnosis include indirect hemagglutination, ELISA, and Casoni test. These tests support diagnosis of which liver pathology?

• A. Hepatic adenoma
• B. Echinococcal cyst
• C. Hepatocellular carcinoma
• D. Cholangiocarcinoma

Answer: (B)

These serologic tests specifically target echinococcosis, hydatid disease caused by Echinococcus species. The liver is a common site for hydatid cysts. Indirect hemagglutination and ELISA detect antibodies against hydatid cyst antigens, helping confirm infection, while the Casoni test (an old intradermal skin test using hydatid fluid) can produce a hypersensitivity reaction in infected individuals. When imaging shows a cystic liver lesion and these antibodies are present, it supports the diagnosis of a hydatid (echinococcal) cyst. The other liver conditions listed are not diagnosed with these serologies, so the best match is an echinococcal cyst.

These serologic tests specifically target echinococcosis, hydatid disease caused by Echinococcus species. The liver is a common site for hydatid cysts. Indirect hemagglutination and ELISA detect antibodies against hydatid cyst antigens, helping confirm infection, while the Casoni test (an old intradermal skin test using hydatid fluid) can produce a hypersensitivity reaction in infected individuals. When imaging shows a cystic liver lesion and these antibodies are present, it supports the diagnosis of a hydatid (echinococcal) cyst. The other liver conditions listed are not diagnosed with these serologies, so the best match is an echinococcal cyst.