What is the second most common testicular metastatic neoplasm?

What is the second most common testicular metastatic neoplasm?

• A. Lymphoma
• B. Prostate cancer
• C. Melanoma
• D. Leukemia

Answer: (D)

Testicular metastasis occurs when cancer cells spread to the testis from a distant primary. After prostate cancer, hematologic malignancies frequently involve the testes, with leukemia commonly presenting as secondary testicular involvement. Leukemic cells reach the testes via the bloodstream and can infiltrate the parenchyma, often producing bilateral enlargement rather than a single distinct mass. On ultrasound, this can appear as diffuse, enlarged testes with increased vascular flow due to infiltration. Clinically, painless testicular enlargement can be a clue in a patient with known leukemia or systemic disease. This pattern of involvement explains why leukemia is considered the second most common testicular metastatic neoplasm.

Testicular metastasis occurs when cancer cells spread to the testis from a distant primary. After prostate cancer, hematologic malignancies frequently involve the testes, with leukemia commonly presenting as secondary testicular involvement. Leukemic cells reach the testes via the bloodstream and can infiltrate the parenchyma, often producing bilateral enlargement rather than a single distinct mass. On ultrasound, this can appear as diffuse, enlarged testes with increased vascular flow due to infiltration. Clinically, painless testicular enlargement can be a clue in a patient with known leukemia or systemic disease. This pattern of involvement explains why leukemia is considered the second most common testicular metastatic neoplasm.