Which is the most common bilateral testicular tumor?

Which is the most common bilateral testicular tumor?

• A. Lymphoma
• B. Germ Cell Tumor
• C. Choriocarcinoma
• D. Leydig Cell Tumor

Answer: (A)

In adult testes, involvement by lymphoma is the most common bilateral tumor. While germ cell tumors are by far the most common overall testicular tumors, they’re usually unilateral. Lymphoma tends to involve both testes, either at presentation or over time, making bilaterality much more common with lymphoma than with other tumor types. On ultrasound, this often shows as diffuse or focal hypoechoic enlargement with vascularity that can affect one or both testes. In contrast, Leydig cell tumors are typically unilateral and hormonally active, and choriocarcinoma, while aggressive, is usually seen as a unilateral germ cell tumor in younger patients. So the bilateral pattern points most strongly to lymphoma.

In adult testes, involvement by lymphoma is the most common bilateral tumor. While germ cell tumors are by far the most common overall testicular tumors, they’re usually unilateral. Lymphoma tends to involve both testes, either at presentation or over time, making bilaterality much more common with lymphoma than with other tumor types. On ultrasound, this often shows as diffuse or focal hypoechoic enlargement with vascularity that can affect one or both testes. In contrast, Leydig cell tumors are typically unilateral and hormonally active, and choriocarcinoma, while aggressive, is usually seen as a unilateral germ cell tumor in younger patients. So the bilateral pattern points most strongly to lymphoma.