Which statement is true about the pathology of FNH?

Which statement is true about the pathology of FNH?

• A. Contains all normal parenchymal components, except portal venous structures
• B. Is always encapsulated
• C. Presents with abnormal LFTs
• D. Is typically associated with cirrhosis

Answer: (A)

FNH is a benign liver lesion characterized by nodules of normal-appearing hepatocytes with a central scar and abnormal arterial supply. A defining histologic feature is that the lesion preserves the normal parenchymal components—hepatocytes and biliary ducts—but lacks portal venous structures within the lesion. In other words, portal venous structures are not present, while the hepatic cells and bile ducts are still recognizable. This pattern helps distinguish FNH from other focal liver lesions. The lesion is not defined by a true capsule, and patients typically have normal liver function tests with no association to cirrhosis.

FNH is a benign liver lesion characterized by nodules of normal-appearing hepatocytes with a central scar and abnormal arterial supply. A defining histologic feature is that the lesion preserves the normal parenchymal components—hepatocytes and biliary ducts—but lacks portal venous structures within the lesion. In other words, portal venous structures are not present, while the hepatic cells and bile ducts are still recognizable. This pattern helps distinguish FNH from other focal liver lesions. The lesion is not defined by a true capsule, and patients typically have normal liver function tests with no association to cirrhosis.