Which zone is the predominant site of BPH?

Which zone is the predominant site of BPH?

• A. Peripheral
• B. Central
• C. Transitional
• D. Periurethral Glandular

Answer: (C)

BPH mainly originates in the transitional zone, the part of the prostate that wraps around the prostatic urethra. As men age, this zone undergoes hyperplasia of both epithelial and stromal components, forming nodules that encroach on the urethral lumen and lead to bladder outlet obstruction. The peripheral zone, by comparison, is where most cancers arise, not BPH, and the central zone is less commonly involved. In imaging terms, the inner, urethra-surrounding tissue enlarges due to transitional zone hyperplasia, while the outer peripheral zone remains relatively spared. So the transitional zone is the predominant site of BPH.

BPH mainly originates in the transitional zone, the part of the prostate that wraps around the prostatic urethra. As men age, this zone undergoes hyperplasia of both epithelial and stromal components, forming nodules that encroach on the urethral lumen and lead to bladder outlet obstruction. The peripheral zone, by comparison, is where most cancers arise, not BPH, and the central zone is less commonly involved. In imaging terms, the inner, urethra-surrounding tissue enlarges due to transitional zone hyperplasia, while the outer peripheral zone remains relatively spared. So the transitional zone is the predominant site of BPH.